Wheat millfeeds are economically most important in high-protein dairy and beef cattle supplements and in poultry rations with metabolizable energy requirements of less than 1,300 kilocalories per pound of ration. Economic analysis suggests that the market undervalues wheat millfeeds in dairy and beef cattle supplements. Also, if the biological availability of the naturally occurring nutrients in millfeeds could be improved, their value in high-energy poultry and swine rations would be increased. To create and maintain a market demand for improved millfeeds would require adoption and enforcement of nutritional standards for these products and a concerted promotional and educational campaign to convince potential users of their worth. These conclusions are based on an economic evaluation of wheat millfeeds in a variety of livestock rations in four different market locations and time periods.