Economic analysis of plant species utilized for Infant and Maternal Health Care (IMHC) in Ogun State was investigated. Multi-stage sampling procedure with three stages design was adopted for this study. Data were obtained with structured questionnaire administered to two categories of respondents; plant species collectors (30); plant species traders (70) giving a sample size of 100. Descriptive and inferential statistical tools were used to analyze the data. The result showed that the mean age of categories of the respondents were 46 years and 44 years for plant species collectors and traders respectively. The two categories of respondent were literate. There were more men (93.3%) in collection activities while there are more women in the trading activities (62.86%). The sales of the plant species were profitable with an average net profit of N60,309.21 and N 58,571.09/month/respondent for plant species collectors and traders respectively. Household size and years of experience in the business significantly affect the net returns of the plants species collectors and traders at p<0.01 respectively. Improve on skill in entrepreneurship of trade in herbal sells has been suggested to promote and increase the income from the sales of the plant species.