Thirty-five empirical studies of factors influencing business location and/or regional economic growth are reviewed. Differences in methodology among the studies are described, and several methodological issues are discussed. Regional characteristics that have been hypothesized to affect regional growth and/or business location are identified, and the results of these studies with regard to the effects of these regional characteristics are discussed. Few results are found to be consistent across studies. Some suggestions are offered about methodological issues and regional characteristics to be considered in future studies of regional economic growth and/or business location.