Recently many industrial sectors in Uzbekistan have been steadily developing. However, in remote regions, like Khorezm, the development of industry, especially agroprocessing industry remains slow. Fruits and vegetables sector can be the main factor for the development of the regional economy in the condition of natural resource scarcity. This paper describes the development of fruits and vegetables s ector in the Khorezm region over the last two decades. Moreover, the SWOT analysis and assessment potentials of the fruits and vegetables value chain in development of the regional economy are reviewed in the current paper.