This paper estimates the demand for corn and soybean shipments on the Ohio River during the 1992-2004 period. Using monthly data, OLS (with Newewy-West standard errors) parameters estimates were obtained for the explanatory variables. Results indicate that Ohio River corn and soybean shipments are significantly and positively affected by one month lagged shipments, corn and soybean stocks in the Ohio River production region, and corn and soybean exports from lower Mississippi River Gulf ports. Some empirical support was found for a significant negative relationship between Ohio River corn and soybean shipments and ocean shipping freight rates from lower Mississippi River Gulf ports to Japan. Indiana corn prices did not significantly affect Ohio River corn and soybean shipments.