Village-level economy is not only the important foundation for promoting grass-roots agricultural and rural modernization, but also an essential guarantee for sustainable development of small scale economy of rural farmer households. Research on this field will play a significant role in rural economic development of Guizhou Province. Taking the observation data from 1999 to 2009 in 10 fixed observation villages in Guizhou Province, we carried out empirical survey and analysis on land scale and use structure, scale and composition of fixed assets for production, level and composition of operational income, and level and composition of financial revenue and expenditure at village level. Finally, we put forward conclusions and recommendations.