Firstly, it is briefly introduced that Guangxi characteristic economic agricultural products are currently characterized by typical regional features and strong competitiveness. Then, Guilin is taken as an example, the problems existing in constructing the supply chain and brand of Guilin characteristic economic agricultural products are pointed out after the analysis of its current situations, the problems include weak agricultural production infrastructure, weak deep products processing capacity, low modernization level of storage and transportation as well as short of fixed marketing channels; meanwhile, brand construction faces the problems of little top brands and few differentiated products. Finally, some measures are proposed to solve these problems from the perspectives of establishing the management idea of agricultural products supply chain and enhancing the awareness to protect agricultural products brand, it is also suggested that these measures be extended to the whole Guangxi autonomous region in order to explore the way of the development of Guangxi characteristic agriculture.