We set up the evaluation index system of the sustainable development ability of grain production on the basis of the overall analysis of grain production trend in Sichuan Province. And then we evaluate the sustainable development ability of grain production from 1990 to 2006 in Sichuan Province by adopting the method of principal component analysis. Result shows that the sustainable development ability of grain production has improved steadily, but there are some hidden troubles such as frequently changes of grain yield and gradually decrease of total farmland. Cluster analysis method is used to study on the sustainable development ability of grain production of 21 cities of Sichuan Province in the year 2006. result shows that grain production levels in different areas of Sichuan Province are similar and complementary. Finally, we put forward some proposals on how to improve the sustainable development ability of grain production.