This report presents relevant statistics that highlight the economic activity of the U.S. seed industry. The focus of this report is on the four main U.S. crops: corn, soybean, wheat, and cotton. The report contains three sections. The first is related to the U.S. seed market’s size based on seed sales and expenditures. The second section examines industry investment in research and development (R&D) activity in terms of both budget and human resources. The final section illustrates the impact of the seed industry in terms of intellectual property development, improved productivity, and other benefits. This report focuses on using publicly available data to examine these three areas. In addition, the report presents the results of a survey conducted among American Seed Trade Association (ASTA) members that helped fill some gaps in publicly available information. The report ends with identification of deficiencies in the industry data that could be improved with more study and/or reporting from the industry.