The paper discusses recent national trends in pesticide use in major crop production, identifying major national shifts in pesticide use between 1960 and 2007 by commodity and specific trends in herbicide and insecticide use in corn, cotton, and soybeans. The paper also shows how hedonic methods are used to calculate quality-adjusted price changes and implicit prices of the quality characteristics of pesticides for 1960 through 2007. In addition, the paper examines quality-adjusted price and quality trends in key corn and cotton states, and examines the major forces driving the pesticide trends.