This paper presents a research agenda on innovation through (international) food supply chains and networks in developing countries. It derives major topics from a multi-perspective view on international food chains (economic, technology, social/legal and environment) and from different theoretical streams dealing with chains and networks (Supply Chain Management, Industrial Organization theory and Network Theory). Three agri-supply chain projects in developing countries (Thailand, South-Africa, Ghana) are analyzed to identify focus areas in supply chain development projects and important gaps. These projects were collaborative actions between companies and research institutes to initiate international supply chain development.