In order to study the effect of 30% Tiange multifunctional pesticide-fertilizer on sugarcane pests and sugarcane yield, the field test was conducted with conventional compound fertilizer and 3% carbofuran fertilizer granules as control. The results showed that 30% Tiange multifunctional pesticide-fertilizer could effectively suppress some pests such as sugarcane borer, thrip, aphid and cockchafer. 90 d after pesticide-fertilizer application, the sugarcane withered heart rate was 1.55% and 2.55% in the two test points, respectively, significantly lower than the rate of 15.40% and 19.40% under control. Before harvest, the sugarcane borer damage rate in the two test points under pesticide-fertilizer treatment was 8.70% and 9.47%, respectively, significantly lower than the rate of 34.50% and 33.50% under control, and the sugarcane yield was 21.16% and 22.14% higher than under control, respectively. 30% Tiange multifunctional pesticide-fertilizer had nutritional and insecticidal effect, which could help to achieve sugarcane pesticide-fertilizer integration and save labor and costs.