The purpose of the article is to analyze the innovative forms of bioeconomy in the region. Due to the aim of the research, the main tasks are the following: to characterize such forms of innovative infractructure as business incubator, technopark, technopolis and cluster; to show the relationship between the evolution of the region and implementation of bioeconomy principles within this region; to investigate the successful experience of different countries concerning the establishment of innovative structures based on biotechnology, to explore the specific conditions of bioeconomy development in Ukraine. The paper contains the general characteristics of the bioeconomy as the economy based on the use of renewable biological resources. Exploring this realm of economy there was used scientific material of various domestic and foreign researchers, analytics and practicians as L. I. Fedulova, K. I. Fedulova, O. M. Anisimova, O. I. Didchenko, K. McCormick, N. Kautto, S. Hilgartner, L. Lewidow and international sources of information such as Communication from the Commission to the European Parliament, the Council, the European Economic and Social Committee and the Committee of the Regions. Preparing the study there were used such scientific methods as analysis, synthesis, generalization, explanation, classification. The article shows the importance of biotechnology using in the region that was confirmed by the world experience. We believe that the main objects of strong activation of biotech sector in the region are the bioclusters. They have the most comprehensive and highest efficiency in terms of uniting the efforts of stakeholders. It is confirmed by the experience of many countries. So, the bioeconomy serves as a new part of the national economy, which has unlimited possibilities for prosperity in the region of its localization through the various innovative forms of expression.