The article investigates the features of investment activity in the region with the reference of bioeconomy. The concept of “bioeconomy” is determined. The significance of the introduction of this concept in the 21st century is proved. The idea of “green” economy as a part of “bioeconomy” is outlined. The notion “green” investments, their value, involvement peculiarities in the regional economy, priority areas for investment are described. The efficiency of investing 2% of world GDP in bioeconomy is analyzed. The cluster model of regional development with region’s ecobrand forming is offered. Formation of clusters increases the investment attractiveness of the region, enhances its competitiveness and increases the amount of investment.