This paper examines pesticide1 markets and regulations in Ghana. This study explores progress to date in Ghana’s country-level implementation of ECOWAS regional pesticide policies. As part of a seven-country set of comparative case studies, this work collectively aims to explore the reasons for uneven rates of country implementation of regional agricultural input policies. West African countries have long recognized their strong regional interdependencies in agricultural and food markets. For many centuries, long distance trading routes have linked different agro-ecological zones within the region. In more recent years, cross-border movements of people, livestock, farm inputs and outputs have underscored the importance of regional interdependencies for ensuring food security.