The main objective of this paper is to identify the differentiation of factors determining the variability of milk production in the European Union macro-regions with a predominance of intensive and extensive production. Classification of regions is based on the analysis of the diversity of dairy farms FADN in the regions of the European Union, which was determined by the agglomeration cluster analysis using Ward method. In order to highlight the determinants of production factor analysis was performed. On the basis of the results, there were factors that have a decisive impact on milk production in dairy farms from regions with a predominance of intensive and extensive production model identified.