Pallets, crates, and dunnage made of wood are commonly used packaging materials in international trade. Our objective was to use data collected by the United States Department of Agriculture (USDA) to discuss the current role of wood packaging material (WPM) in the movement of pest species into and within the Greater Caribbean Region. For both maritime and air cargo, significant differences were found between countries of origin in terms of the percentage of shipments that contain WPM. A list of species intercepted on WPM at U.S. ports-of-entry after full enforcement of the international standard ISPM 15, as well as a list of species associated with WPM that have the potential to establish in the Greater Caribbean Region, are presented.