The world of business has become an extremely dynamic environment in which the only constant is change. In Latin America and the Caribbean, the situation is obliging the actors to enhance their strategies and visions for correcting the long-standing weaknesses of the productive sectors. The concept of entrepreneurship, meaning the individual or collective capacity to develop sustainable enterprises, is an important focus of research that is making it possible to undertake concrete actions in aid of the productive sectors. This article looks at the ideas involved in entrepeneurship and the important function that the latter is playing in the overall development of our hemisphere. It also considers ways of promoting enterprise development as part of the strategies for agrifood chains and rural territories.