In this paper we use the TOA-MD model to test climate change impacts and adaptation strategies with socioeconomic, survey data from the upper White Volta Basin of Ghana. Combining simu-lated and expected crop and livestock yields under three different climate scenarios, the econom-ic impact of climate change to 2050 is analysed. We find that livelihood outcome variables like income and poverty levels as well as adoption rates are sensitive to the different climate scenari-os. Most particularly, introducing an intensive and extended (I&E) irrigation technology as a climate change adaptation strategy offsets some negative climate change impacts and improves income but not poverty rates in the area. The results are useful in providing spatiotemporarily-specific policy recommendations on the potential impacts of climate change and the economic outcomes associated with different adaptation strategies.