In order to provide an objective and scientific theoretical basis for rational distribution of wheat growth in Yunnan Province, according to the relationship between Yunnan weather conditions and wheat growth adaptability, a study on eco-climate type regionalization of wheat growing areas in Yunnan was conducted using principal component analysis and GIS technology. The results show that Yunnan Province could be divided into four types, namely southern warm and humid wheat growing area, central semi-arid wheat growing area, central semi-humid wheat growing area and north-central cold wheat growing area.