The sustainability of small and medium-sized enterprises (SMEs) is constantly challenged on today’s dynamic operating environment. Evolving regulatory trends, difficult economic conditions, and diminishing natural resources, pose serious questions for all players across the food system. Technological innovation, as a means of ensuring future sustainability in the same in the face of such challenges, has been the focus of significant government investment in Ireland. This paper, aims to facilitate a greater understanding of the motivations and barriers influencing the decision by food SMEs to invest in technological innovation emanating from research conducted in publicly-funded research institutes.