Hanyuan Prickly Ash is a type of GI product with a very deep cultural intension. From such humanistic factors as name origin, historical origin, fame, cultivation technology, and management measure, and such natural factors as climatic environment and soil conditions, this paper analysis key factors for protection of GI product Hanyuan Prickly Ash. Then it discusses about industrial development of Hanyuan Prickly Ash from suitable planting areas and climate. It proposes that we should gradually raise safety and hygienic indexes, revise and implement local standards, strengthen popularization of harmless production technologies and quality control of product, promote “enterprise + base” industrial model, and implement government marketing of brand and industry.