We adopt sampling method combined with questionnaire to research tobacco agricultural development in Baise City of Guangxi Province. Survey results show that there are problems of inadequate propaganda; guidance and training effort; unreasonable rotation system; backward tobacco baking technologies; low specialized service level; constant increase of costs for means of production and labor employment; low information management level; and frequent occurrence of production accidents. Therefore, it is required to strengthen propaganda and training; enhance technical support; scientifically develop tobacco farmers' cooperative organizations; improve service quality; save labor and reduce cost; improve information management level; reduce institutional operation cost; reinforce guidance of safe production, to promote healthy and orderly development of tobacco agriculture in Guangxi and even in the whole country in the environment of information asymmetry.