Guangxi Beibu Gulf Economic Zone has taken the initiative to explore how to promote public administration of interregional local governments and achieved some success in recent years. However, there are still many problems as follows: the cooperation never goes deep; the cooperative governance is devoid of necessary system guarantee and information exchange and share platform We analyze the status quo of cooperation in regional intergovernmental public administration as follows, it integrates the hierarchy power of government; it sponsors the forum for strengthening public administration and deepening cooperation in Beibu Gulf Economic Zone; it accelerates regional transportation system building; it sets up public administration institution; it quickens the pace of innovation of management and system in Beibu Gulf Economic Zone. Finally we put forward the path to construction of regional government cooperative governance so as to promote sustainable regional development as follows, construct the composite regional administrative cooperative governance model; construct the regional administrative network organization governance model; construct regional administrative special-project-based intergovernmental cooperative governance model; construct long-term flexible regional administrative cooperative mechanism.